1️⃣ DKDComboMiner DM · 당뇨신증
디케이디콤보마이너 — DKD 다약물 조합 가설 채굴기 (Python CLI · 235,872 cell)
DKD 약물 23종 × KDIGO 18 stage × biomarker 7 × population 8 5D ontology → 합성 PubMed/CTG/FAERS/한국 코호트 cross-reference → 미탐색 (drug-combo × stage × biomarker × population) cell ranking + grant-ready hypothesis card + KDA/KSAD abstract 초안.
rank --top 8
hypothesis card (top-1)
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2️⃣ MASLDPharmacoGeno MASLD
매슬드파마코지노 — MASLD genotype × 약물 × outcome 5D pharmacogenomics 가설 허브 (Python CLI · 3,375 cell)
SNP 5(PNPLA3·TM6SF2·HSD17B13·MBOAT7·GCKR) × 약물 9(resmetirom·efruxifermin·pegozafermin·lanifibranor·semaglutide·tirzepatide·survodutide·pioglitazone·비타민E) × outcome 5 × 식이 5 × ethnic 3 ontology → 합성 PubMed/GWAS/gnomAD/CTG cross-reference → 미탐색 cell ranking + 한국 lean MASLD focus mode + AASLD/EASL abstract 초안.
rank --top 8
--korean-lean
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3️⃣ ObesityCVHypoMap Obesity · CV
오베시티시브이하이포맵 — 항비만약물 × CV outcome subtype × phenotype 매개경로 가설맵 (Python CLI · 495 cell)
약물 9(semaglutide·liraglutide·tirzepatide·retatrutide·CagriSema·orforglipron·MariTide·setmelanotide·pioglitazone) × CV subtype 11(MACE 4 + HF 4 + AF 3) × phenotype 5 × mediation 5 6D ontology → 합성 PubMed/CTG/FAERS/medRxiv cross-reference → top hypothesis card + VanderWeele/Imai-Keele-Tingley mediation framework + 한국 RWE 가능성 score + AHA/KSSO abstract 초안.
rank --top 8
summary
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