{
  "mediators": [
    {"id": "FGF21", "name_ko": "FGF21", "class": "hormone", "chebi": "UMLS:C1452540", "primary_source": "liver"},
    {"id": "FGF19", "name_ko": "FGF19", "class": "hormone", "chebi": "UMLS:C1565762", "primary_source": "gut"},
    {"id": "GDF15", "name_ko": "GDF15", "class": "cytokine", "chebi": "UMLS:C0951471", "primary_source": "liver/stress"},
    {"id": "adiponectin", "name_ko": "아디포넥틴", "class": "adipokine", "primary_source": "adipose_subcutaneous"},
    {"id": "leptin", "name_ko": "렙틴", "class": "adipokine", "primary_source": "adipose_visceral"},
    {"id": "resistin", "name_ko": "레지스틴", "class": "adipokine", "primary_source": "adipose_visceral"},
    {"id": "TNF_alpha", "name_ko": "TNF알파", "class": "cytokine", "primary_source": "immune_system"},
    {"id": "IL6", "name_ko": "IL-6", "class": "cytokine", "primary_source": "skeletal_muscle/immune_system"},
    {"id": "IL17A", "name_ko": "IL-17A", "class": "cytokine", "primary_source": "immune_system"},
    {"id": "IL18", "name_ko": "IL-18", "class": "cytokine", "primary_source": "immune_system"},
    {"id": "MCP1", "name_ko": "MCP-1", "class": "chemokine", "primary_source": "adipose_visceral"},
    {"id": "CXCL10", "name_ko": "CXCL10", "class": "chemokine", "primary_source": "liver"},
    {"id": "irisin", "name_ko": "이리신", "class": "myokine", "primary_source": "skeletal_muscle"},
    {"id": "myostatin", "name_ko": "마이오스타틴", "class": "myokine", "primary_source": "skeletal_muscle"},
    {"id": "BAIBA", "name_ko": "BAIBA", "class": "myokine_metabolite", "primary_source": "skeletal_muscle"},
    {"id": "osteocalcin", "name_ko": "오스테오칼신", "class": "osteokine", "primary_source": "bone"},
    {"id": "sclerostin", "name_ko": "스클레로스틴", "class": "osteokine", "primary_source": "bone"},
    {"id": "lipocalin2", "name_ko": "리포칼린-2", "class": "hepatokine", "primary_source": "liver"},
    {"id": "fetuinA", "name_ko": "페투인-A", "class": "hepatokine", "primary_source": "liver"},
    {"id": "selenoprotein_P", "name_ko": "셀레노프로틴-P", "class": "hepatokine", "primary_source": "liver"},
    {"id": "ANGPTL4", "name_ko": "ANGPTL4", "class": "hepatokine", "primary_source": "liver"},
    {"id": "ANGPTL8", "name_ko": "ANGPTL8 (베타트로핀)", "class": "hepatokine", "primary_source": "liver"},
    {"id": "GLP1", "name_ko": "GLP-1", "class": "incretin", "primary_source": "gut/pancreas"},
    {"id": "GIP", "name_ko": "GIP", "class": "incretin", "primary_source": "gut"},
    {"id": "PYY", "name_ko": "PYY", "class": "gut_hormone", "primary_source": "gut"},
    {"id": "ghrelin", "name_ko": "그렐린", "class": "gut_hormone", "primary_source": "gut/stomach"},
    {"id": "bile_acid_TCA", "name_ko": "타우로콜산", "class": "bile_acid", "primary_source": "liver/gut"},
    {"id": "TMAO", "name_ko": "TMAO", "class": "metabolite", "primary_source": "gut_microbiome"},
    {"id": "indole3acetate", "name_ko": "인돌-3-아세테이트", "class": "metabolite", "primary_source": "gut_microbiome"},
    {"id": "LPS", "name_ko": "LPS(내독소)", "class": "PAMP", "primary_source": "gut_microbiome"},
    {"id": "SCFA_butyrate", "name_ko": "부티르산(SCFA)", "class": "metabolite", "primary_source": "gut_microbiome"},
    {"id": "ceramide_C16", "name_ko": "C16-세라마이드", "class": "lipid", "primary_source": "liver/adipose"},
    {"id": "DAG", "name_ko": "DAG", "class": "lipid", "primary_source": "liver"},
    {"id": "lysoPC", "name_ko": "lysoPC", "class": "lipid", "primary_source": "liver"},
    {"id": "miR122", "name_ko": "miR-122", "class": "miRNA", "primary_source": "liver"},
    {"id": "miR34a", "name_ko": "miR-34a", "class": "miRNA", "primary_source": "liver/adipose"},
    {"id": "miR103", "name_ko": "miR-103", "class": "miRNA", "primary_source": "adipose"},
    {"id": "exosome_AdipoExos", "name_ko": "지방세포유래 엑소좀", "class": "exosome", "primary_source": "adipose_visceral"},
    {"id": "exosome_HepExos", "name_ko": "간세포유래 엑소좀", "class": "exosome", "primary_source": "liver"},
    {"id": "BMP4", "name_ko": "BMP4", "class": "growth_factor", "primary_source": "BAT/adipose"},
    {"id": "BMP7", "name_ko": "BMP7", "class": "growth_factor", "primary_source": "BAT"},
    {"id": "T3", "name_ko": "T3", "class": "thyroid_hormone", "primary_source": "thyroid"},
    {"id": "rT3", "name_ko": "rT3(역T3)", "class": "thyroid_hormone", "primary_source": "liver"},
    {"id": "estradiol", "name_ko": "에스트라디올", "class": "sex_hormone", "primary_source": "gonad"},
    {"id": "testosterone", "name_ko": "테스토스테론", "class": "sex_hormone", "primary_source": "gonad"},
    {"id": "SHBG", "name_ko": "SHBG", "class": "transport_protein", "primary_source": "liver"},
    {"id": "cortisol", "name_ko": "코르티솔", "class": "glucocorticoid", "primary_source": "adrenal/HPA"},
    {"id": "insulin", "name_ko": "인슐린", "class": "hormone", "primary_source": "pancreas"},
    {"id": "glucagon", "name_ko": "글루카곤", "class": "hormone", "primary_source": "pancreas"},
    {"id": "amylin", "name_ko": "아밀린", "class": "hormone", "primary_source": "pancreas"},
    {"id": "BCAA_leucine", "name_ko": "분지쇄아미노산(루신)", "class": "metabolite", "primary_source": "muscle/diet"},
    {"id": "kynurenine", "name_ko": "키누레닌", "class": "metabolite", "primary_source": "liver/immune"},
    {"id": "lactate", "name_ko": "락테이트", "class": "metabolite", "primary_source": "muscle/liver"},
    {"id": "BHB", "name_ko": "베타하이드록시부티르산", "class": "ketone_body", "primary_source": "liver"},
    {"id": "uric_acid", "name_ko": "요산", "class": "metabolite", "primary_source": "liver"},
    {"id": "homoarginine", "name_ko": "호모아르기닌", "class": "metabolite", "primary_source": "kidney/liver"},
    {"id": "FGF23", "name_ko": "FGF23", "class": "phosphatonin", "primary_source": "bone"},
    {"id": "klotho", "name_ko": "Klotho", "class": "anti_aging", "primary_source": "kidney"},
    {"id": "ANP", "name_ko": "ANP", "class": "natriuretic_peptide", "primary_source": "heart"},
    {"id": "BNP", "name_ko": "BNP", "class": "natriuretic_peptide", "primary_source": "heart"},
    {"id": "neuregulin4", "name_ko": "Neuregulin-4", "class": "BAT_kine", "primary_source": "BAT"}
  ]
}