{
  "interactions": [
    {"source": "FGF21", "target": "FGFR1c+KLB", "evidence": "STRING:0.92", "pathway": "Reactome:R-HSA-9640468", "kegg": "hsa04015"},
    {"source": "FGF19", "target": "FGFR4+KLB", "evidence": "STRING:0.95", "pathway": "Reactome:R-HSA-9640468"},
    {"source": "GLP1", "target": "GLP1R", "evidence": "STRING:0.99", "pathway": "Reactome:R-HSA-381676", "kegg": "hsa04024"},
    {"source": "adiponectin", "target": "ADIPOR1", "evidence": "STRING:0.96", "pathway": "Reactome:R-HSA-9645722"},
    {"source": "leptin", "target": "LEPR", "evidence": "STRING:0.98", "pathway": "Reactome:R-HSA-9645722"},
    {"source": "TNF_alpha", "target": "TNFR1", "evidence": "STRING:0.99", "pathway": "Reactome:R-HSA-75893"},
    {"source": "IL17A", "target": "IL17RA", "evidence": "STRING:0.97", "pathway": "Reactome:R-HSA-448424"},
    {"source": "irisin", "target": "AlphaV/Beta5_integrin", "evidence": "STRING:0.81", "pathway": "Reactome:R-HSA-216083"},
    {"source": "BAIBA", "target": "PPARalpha", "evidence": "STRING:0.78", "pathway": "Reactome:R-HSA-1989781"},
    {"source": "osteocalcin", "target": "GPRC6A", "evidence": "STRING:0.82", "pathway": "Reactome:R-HSA-9617828"},
    {"source": "TMAO", "target": "PERK_stress", "evidence": "STRING:0.74", "pathway": "Reactome:R-HSA-381119"},
    {"source": "LPS", "target": "TLR4", "evidence": "STRING:0.99", "pathway": "Reactome:R-HSA-168164", "kegg": "hsa04620"},
    {"source": "bile_acid_TCA", "target": "FXR_NR1H4", "evidence": "STRING:0.96", "pathway": "Reactome:R-HSA-192105"},
    {"source": "ceramide_C16", "target": "PP2A", "evidence": "STRING:0.79", "pathway": "Reactome:R-HSA-1483206"},
    {"source": "T3", "target": "THRB", "evidence": "STRING:0.99", "pathway": "Reactome:R-HSA-383280"},
    {"source": "FGF21", "target": "UCP1_BAT", "evidence": "STRING:0.85", "pathway": "Reactome:R-HSA-163200"},
    {"source": "myostatin", "target": "ACVR2B", "evidence": "STRING:0.94", "pathway": "Reactome:R-HSA-201451"},
    {"source": "exosome_AdipoExos", "target": "miR_transfer_liver", "evidence": "BioGRID_mock:high"},
    {"source": "exosome_HepExos", "target": "miR_transfer_endothel", "evidence": "BioGRID_mock:medium"},
    {"source": "neuregulin4", "target": "ERBB4", "evidence": "STRING:0.88", "pathway": "Reactome:R-HSA-1227986"}
  ]
}