{
  "_note": "합성 evidence. PMID/NCT는 시연용 mock 식별자. 실제 검색 결과 아님.",
  "pubmed_evidence": [
    {"drug": "semaglutide_2_4", "cv_subtype": "mi", "phenotype": "t2dm_pos", "n_papers": 42, "top_pmid_mock": "PMID:MOCK00001", "year_range": "2018-2024"},
    {"drug": "semaglutide_2_4", "cv_subtype": "hfpef", "phenotype": "t2dm_pos", "n_papers": 18, "top_pmid_mock": "PMID:MOCK00002", "year_range": "2022-2025"},
    {"drug": "semaglutide_2_4", "cv_subtype": "hfpef", "phenotype": "lean_diabetic_asian", "n_papers": 1, "top_pmid_mock": "PMID:MOCK00003", "year_range": "2024"},
    {"drug": "tirzepatide", "cv_subtype": "hfpef", "phenotype": "t2dm_pos", "n_papers": 24, "top_pmid_mock": "PMID:MOCK00010", "year_range": "2023-2025"},
    {"drug": "tirzepatide", "cv_subtype": "rv_dysfunction", "phenotype": "osa_pos", "n_papers": 0},
    {"drug": "tirzepatide", "cv_subtype": "af_paroxysmal", "phenotype": "lean_diabetic_asian", "n_papers": 0},
    {"drug": "retatrutide", "cv_subtype": "hfpef", "phenotype": "sarcopenic", "n_papers": 0},
    {"drug": "cagrisema", "cv_subtype": "af_persistent", "phenotype": "post_bariatric", "n_papers": 0},
    {"drug": "orforglipron", "cv_subtype": "ischemic_stroke", "phenotype": "lean_diabetic_asian", "n_papers": 0},
    {"drug": "maritide", "cv_subtype": "hfmref", "phenotype": "sarcopenic", "n_papers": 0},
    {"drug": "setmelanotide", "cv_subtype": "cv_death", "phenotype": "post_bariatric", "n_papers": 0},
    {"drug": "pioglitazone", "cv_subtype": "ischemic_stroke", "phenotype": "lean_diabetic_asian", "n_papers": 6, "top_pmid_mock": "PMID:MOCK00050", "year_range": "2010-2022"}
  ],
  "ctg_active_trials": [
    {"drug": "semaglutide_2_4", "cv_subtype": "hfpef", "nct_mock": "NCT_MOCK_2001", "korea_sites": 3},
    {"drug": "tirzepatide", "cv_subtype": "hfpef", "nct_mock": "NCT_MOCK_2002", "korea_sites": 5},
    {"drug": "tirzepatide", "cv_subtype": "mi", "nct_mock": "NCT_MOCK_2003", "korea_sites": 4},
    {"drug": "retatrutide", "cv_subtype": "cv_death", "nct_mock": "NCT_MOCK_2004", "korea_sites": 2},
    {"drug": "cagrisema", "cv_subtype": "mi", "nct_mock": "NCT_MOCK_2005", "korea_sites": 1},
    {"drug": "orforglipron", "cv_subtype": "cv_death", "nct_mock": "NCT_MOCK_2006", "korea_sites": 2}
  ],
  "faers_signals": [
    {"drug": "semaglutide_2_4", "cv_subtype": "af_paroxysmal", "prr": 1.6, "ror": 1.7, "n_reports": 38},
    {"drug": "tirzepatide", "cv_subtype": "af_paroxysmal", "prr": 1.9, "ror": 2.0, "n_reports": 22},
    {"drug": "tirzepatide", "cv_subtype": "rv_dysfunction", "prr": 2.4, "ror": 2.6, "n_reports": 9},
    {"drug": "retatrutide", "cv_subtype": "af_persistent", "prr": 2.1, "ror": 2.3, "n_reports": 7},
    {"drug": "cagrisema", "cv_subtype": "rv_dysfunction", "prr": 2.0, "ror": 2.1, "n_reports": 5},
    {"drug": "setmelanotide", "cv_subtype": "af_paroxysmal", "prr": 3.0, "ror": 3.2, "n_reports": 4}
  ],
  "preprint_signals": [
    {"drug": "tirzepatide", "cv_subtype": "hfpef", "phenotype": "lean_diabetic_asian", "server": "medRxiv", "doi_mock": "10.1101/MOCK.2025.04.001"},
    {"drug": "retatrutide", "cv_subtype": "hfpef", "phenotype": "sarcopenic", "server": "medRxiv", "doi_mock": "10.1101/MOCK.2025.03.014"},
    {"drug": "orforglipron", "cv_subtype": "ischemic_stroke", "phenotype": "lean_diabetic_asian", "server": "medRxiv", "doi_mock": "10.1101/MOCK.2025.02.022"}
  ]
}