{
  "_disclaimer": "Placeholder reference values. Replace with KDA/KAID published Korean data before use.",
  "_source": "Synthetic placeholder informed by ATTD 2022 consensus + assumed Korean closed-loop pilot",
  "primary_outcome": "delta_TIR_pct (between-group difference in time-in-range, %)",
  "default": {
    "delta_TIR_pct": 5.0,
    "sd_TIR_pct": 12.0,
    "comment": "Conservative default for parallel RCT, AID vs SAP comparator"
  },
  "hba1c_tertiles": [
    {
      "tertile": "low",
      "hba1c_range": "<7.0%",
      "delta_TIR_pct": 3.5,
      "sd_TIR_pct": 10.0,
      "rationale": "Ceiling effect: less room to improve TIR"
    },
    {
      "tertile": "mid",
      "hba1c_range": "7.0-8.5%",
      "delta_TIR_pct": 6.0,
      "sd_TIR_pct": 12.0,
      "rationale": "Largest expected effect (sweet spot for AID benefit)"
    },
    {
      "tertile": "high",
      "hba1c_range": ">8.5%",
      "delta_TIR_pct": 8.5,
      "sd_TIR_pct": 14.5,
      "rationale": "Greater absolute effect, but larger variance"
    }
  ]
}